CBIO · 7 official subcategories7 个官方子类别
Computational Biology and Bioinformatics
计算生物学与生物信息学
Studies that primarily focus on the discipline and techniques of computer science and mathematics as they relate to biological systems. This includes the development and application of data-analytical and theoretical methods, mathematical modeling and computational simulation techniques to the study of biological, behavior, and social systems.
以计算机科学与数学的方法和技术为主要手段来研究生物系统。包括开发并应用数据分析方法、理论方法、数学建模和计算模拟技术，用于研究生物系统、行为系统和社会系统。
368
finalist projects入围项目
5.5%
of all finalists占全部入围
28.5%
grand-award rate大奖率
3.8%
first-place or above一等奖及以上
Window 2022-2026. 427 students. 12% of projects are teams.统计窗口 2022-2026。427 人次。团队项目占 12%。
Official Subcategories官方子类别
What belongs in this category这个类别收什么
- MOD计算生物建模Computational BiomodelingStudies that involve computer simulations of biological systems most commonly with a goal of understanding how cells or organism develop, work collectively and survive.对生物系统进行计算机模拟，通常目的是理解细胞或生物体如何发育、如何协同运作、如何存活。
- EPD计算流行病学Computational EpidemiologyThe study of disease frequency and distribution, and risk factors and socioeconomic determinants of health within populations. Such studies may include gathering information to confirm existence of disease outbreaks, developing case definitions and analyzing epidemic data, establishing disease surveillance, and implementing methods of disease prevention and control.研究人群中疾病的发生频率与分布，以及健康的风险因素和社会经济决定因素。可包括收集信息以确认疫情、制定病例定义并分析流行病学数据、建立疾病监测，以及实施防控手段。
- EVO计算演化生物学Computational Evolutionary BiologyA study that applies the discipline and techniques of computer science and mathematics to explore the processes of change in populations of organisms, especially taxonomy, paleontology, ethology, population genetics and ecology.运用计算机科学与数学的方法，探究生物种群的变化过程，尤其涉及分类学、古生物学、行为学、种群遗传学和生态学。
- NEU计算神经科学Computational NeuroscienceA study that applies the discipline and techniques of computer science and mathematics to understand brain function in terms of the information processing properties of the structures that make up the nervous system.运用计算机科学与数学的方法，从神经系统各结构的信息处理特性出发来理解大脑功能。
- PHA计算药理学Computational PharmacologyA study that applies the discipline and techniques of computer science and mathematics to predict and analyze the responses to drugs.运用计算机科学与数学的方法，预测和分析机体对药物的反应。
- GEN基因组学GenomicsThe study of the function and structure of genomes using recombinant DNA, sequencing, and bioinformatics.借助重组 DNA 技术、测序和生物信息学手段，研究基因组的功能与结构。
- OTH其他OtherStudies that cannot be assigned to one of the above subcategories. If the project involves multiple subcategories, the principal subcategory should be chosen instead of Other.无法归入上述任何子类别的研究。如果项目涉及多个子类别，应选择项目的主要子类别，而不是选择“其他”。
Judges are assigned by the subcategory you pick, so choose the primary one rather than "Other" where a project could sit in several. Source: Society for Science.评委是按你所选的子类别分配的，一个项目若能落入多个子类别，应选主要的那个，而不是「Other」。来源：Society for Science 官方。 Official page官方页面
The Numbers数据
Scale, trend and award rate规模、趋势与获奖率
Finalists per year逐年入围项目
Grand-award rate vs all tracks大奖率与全赛道对照
28.5%, Wilson 95% 24%–34%. Grey line: all-track 30.3%.28.5%，Wilson 95% 区间 24%–34%。灰线为全赛道 30.3%。
Grand-award tiers大奖层级分布
| Top award顶级大奖 | 1 |
| First一等 | 10 |
| Second二等 | 15 |
| Third三等 | 25 |
| Fourth四等 | 32 |
Special-award rate 14.8%; combined 36.4%.专项奖率 14.8%；合并口径 36.4%。
These tier counts exclude 2025, whose award text is missing from the official database. The award-winning projects listed below do include 2025, recovered from the grand-award press release, so the two will not add up.层级分布剔除了 2025 年——该年官方库缺奖项文本。下方的获奖作品清单则包含 2025 年（从大奖新闻稿补回），因此两处数字不会相等。
The gap from the all-track rate of 30.3% is not statistically significant (Fisher exact p = 0.513).与全赛道 30.3% 的差距不具统计显著性（Fisher 精确检验 p = 0.513）。
Who Competes Here谁在这个赛道
Countries and schools国家与学校
Top countries and regions入围最多的国家与地区
| Country / region国家/地区 | Projects项目 | Grand rate大奖率 | Won/eligible获奖/评奖 |
|---|---|---|---|
| 美国 | 290 | 31.3% | 71/227 |
| 沙特阿拉伯 | 9 | 14.3% | 1/7 |
| 印度 | 8 | 16.7% | 1/6 |
| 加拿大 | 6 | 40.0% | 2/5 |
| 土耳其 | 4 | 0.0% | 0/4 |
| 泰国 | 4 | 50.0% | 2/4 |
| 波多黎各 | 4 | 0.0% | 0/2 |
| 加纳 | 3 | 0.0% | 0/3 |
| 韩国 | 3 | 0.0% | 0/2 |
| 捷克 | 3 | 50.0% | 1/2 |
| 西班牙 | 3 | 0.0% | 0/2 |
| 以色列 | 3 | 0.0% | 0/3 |
China in this track中国在该赛道
| Region地区 | Projects项目 | Grand rate大奖率 | Won/eligible获奖/评奖 |
|---|---|---|---|
| 大陆 | 1 | 0.0% | 0/1 |
| 澳门 | 1 | 0.0% | 0/1 |
Schools with the most finalists入围最多的学校
| School学校 | Projects项目 |
|---|---|
| University School of Milwaukee | 5 |
| Nikola Tesla STEM High School | 5 |
| Adlai E. Stevenson High School | 5 |
| BASIS San Antonio Shavano Campus | 4 |
| Carmel High School | 4 |
| Little Rock Central High School | 4 |
| William A. Shine Great Neck South High School | 4 |
| Canyon Crest Academy | 3 |
| duPont Manual High School | 3 |
| Detroit Country Day School | 3 |
Rates on fewer than roughly 40 eligible projects carry wide intervals — read them as magnitude, not ranking.评奖口径项目数不足约 40 的比率，置信区间很宽，只能当量级看，不能用于排名。
Award-Winning Projects获奖作品
First place and above, plus recent seconds一等奖及以上，附近两届二等奖
Titles as recorded in the official abstract database. Student names are not shown.标题按官方摘要库原文。不显示学生姓名。
Top award顶级大奖1
- 2023美国BIO-PLEX: An Innovative Biocomputational Approach to Decode the Secrets of the 2022 Mpox ResurgenceDavid H. Hickman High School
First award一等奖12
- 2026美国A Multi-Modal Deep Learning Pipeline Integrating Physics-Informed Neural Networks and 3D Image Processing for Accurate Rupture Prediction and Data-Driven Surgical Planning of Cerebral Aneurysms: Year 3West Shore Junior/Senior High School · 1 special awards 项专项奖
- 2026沙特阿拉伯A Markov Chain Model for Predicting ETI Resistance Breakdown in Tomato–Pseudomonas syringaeRowad High School · 1 special awards 项专项奖
- 2025美国StutterZero: End-to-End Speech Conversion to Transcribe and Correct StuttersMillburn High School
- 2025美国The Novel Role of KRT Proteins as Biomarkers in the Dysregulated Neuroendocrine System of ALS for Early Diagnosis With PT150 as a Novel Multi-Target Neuroprotective TherapeuticArizona College Prep High School / International Academy / Park Tudor School · 3 students 人
- 2024美国A Lens Into Vision: Modeling the Stimuli-Driven Differential Responses of Lobula Columnar Cells in DrosophilaWilliam A. Shine Great Neck South High School · 1 special awards 项专项奖
- 2024美国Novel Drug Discovery Methodology Using Machine Learning for Gene Expression-Based Virtual Screening Predicts Novel Compounds To Reverse Alzheimer's Disease With Applications to Cancer and Longevity by Inhibiting CtBP2 ExpressionBronx High School of Science
- 2023美国Micro-Changing Short Tandem Repeats: Investigating a Novel Genomic Factor of Polymorphism in 10 Human CancersJericho High School · 1 special awards 项专项奖
- 2023美国Improved Generalizability and Performance on Small Datasets Using Hyper-Connected Neural Architectures, C. elegans-Inspired Networks, and Evolutionary ModelingScripps Ranch High School · 2 special awards 项专项奖
- 2022美国COVID-19 Detection on Chest X-Ray Using an Enhanced Neural Network Model: Impact of Network Architecture Complexity, Data Augmentation, and Transfer Learning on ModelF. W. Buchholz High School · 1 special awards 项专项奖
- 2022美国Recurrent Repeat Contractions: Investigating a Novel Genomic Factor of Polymorphism in 10 Human CancersJericho High School
- 2022美国ARIEL: Adversarial Neural Evolution for Unified Variant Forecasting and Proactive Therapeutic DesignMillburn High School · 2 special awards 项专项奖
- 2022泰国CANDraGAT: A Hybrid Fragment-Based Graph Attention Network To Improve Cancer Drug Response PredictionMahidol Wittayanusorn School · 3 students 人
Second award二等奖9 (2025–2026 only)（仅列 2025–2026）
- 2026新加坡Beating the Odds in Drug Discovery With 3DICE: Interpretable 3D Cross-Modal Learning for Drug–Target Interaction Prediction at ScaleRaffles Institution
- 2026加拿大A Multi-Omic “Digital Embryo” Framework to Model Early Human Preimplantation Development In SilicoSaint Theresa of Lisieux Catholic High School · 2 special awards 项专项奖
- 2026美国Biophysical and Genomic Drivers of Targeted Therapy Resistance: Analysis of Growth Dynamics in Non-Small Cell Lung CancerHorace Greeley High School
- 2026美国Designing and Delivering Molecular Glue Degraders for the Total Elimination of Previously Undruggable Pathogenic ProteinsInternational Academy · 2 students 人
- 2026美国A Unified Protein Embedding Model With Local and Global Structural SensitivityLexington High School
- 2025美国StAIR: Stepwise All-Atom Iterative Reconstruction of Large Coarse-Grained Protein StructuresWilliam A. Shine Great Neck South High School
- 2025美国Allosteric Regulation of Ectopically Expressed Olfactory Receptors in Tumor Cells: Ligand-Receptor Topology and Deep Learning-Assisted Drug DiscoveryDublin High School · 2 students 人
- 2025美国Variational Autoencoder Latent Space as a Robust Clinical Classification Tool for Neurodegenerative DiseasesPine Crest School
- 2025美国Modeling Bird Flu Mutation Patterns and Cross-Species Transmission Using Sequence Analysis and a Novel Contrastive Learning and Influence-tree Graph Attention Network (CLIGAT)BASIS Scottsdale
See all 368 projects in this track as a content map →把这个赛道的 368 个项目看成一张内容地图 →
15 candidate topics for Computational Biology and Bioinformatics →计算生物学与生物信息学 的 15 条候选课题 →
All 22 tracks →返回全部 22 个赛道 →
Full data analysis →完整数据分析 →